Press Release •  3/10/2023

Corteva Agriscience Announces Plant Breeding Innovation to Combat Corn Disease

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Novel New Technique Uses CRISPR to Increase Multi-Disease Resistance Using Native Genes

INDIANAPOLIS, Ind., March 10, 2023 — Corteva Agriscience (NYSE: CTVA) today announced a game-changing gene editing technology that will bring added protection to elite corn hybrids is advancing through the company’s R&D pipeline. The early-stage concept uses proprietary technology to package multiple disease-resistant native traits into a single location in the gene to better address the most devastating North American corn diseases facing farmers today.

In 2021, Northern leaf blight, Southern rust, gray leaf spot and anthracnose stalk rot combined to cost North America corn growers more than 318 million bushels in production. By using gene editing to combine and reposition disease resistant traits that already exist within the corn genome, Corteva is able to bolster disease tolerance and minimize production stress. Additionally, the technology could result in healthier plants and increase yield potential even further.

“This transformational technology represents the next generation of plant breeding innovation,” said Sam Eathington, Chief Technology and Chief Digital Officer, Corteva Agriscience. “Our best-in-class gene mapping capabilities have allowed us to identify and optimally position the best native resistant genes in our already high-performing hybrids, so that we can deliver a premium product to farmers.”

As plant disease continues to be a growing concern for farmers, the multi-disease resistance concept is intended to simplify disease management and improve sustainability by reducing the need for additional crop protection product applications. This advancement will also meet Corteva’s sustainable innovation criteria for new products, which are based on the United Nations Sustainable Development Goals.

Additionally, it provides farmers with more freedom to select performance characteristics more in line with their yield goals than having to worry about disease resistance.

Corteva has a long-standing commitment to meeting the rapidly evolving needs of farmers around the world. This breakthrough is another proof point in Corteva’s efforts to provide farmers with more sustainable ways to protect their crop while continuing to safeguard the land, water and air resources that make food production possible.

While this groundbreaking plant breeding approach is initially being applied to the diseases that most concern North American farmers, it has the potential to be scaled to other crops, incorporate other diseases or be otherwise tailored to specific geographies.

The company anticipates this concept to advance to commercialization by the end of the decade.

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About Corteva Agriscience
Corteva, Inc. (NYSE: CTVA) is a publicly traded, global pure-play agriculture company that combines industry-leading innovation, high-touch customer engagement and operational execution to profitably deliver solutions for the world’s most pressing agriculture challenges. Corteva generates advantaged market preference through its unique distribution strategy, together with its balanced and globally diverse mix of seed, crop protection, and digital products and services. With some of the most recognized brands in agriculture and a technology pipeline well positioned to drive growth, the company is committed to maximizing productivity for farmers, while working with stakeholders throughout the food system as it fulfills its promise to enrich the lives of those who produce and those who consume, ensuring progress for generations to come. More information can be found at www.corteva.com.

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Cautionary Statement on Forward-Looking Statements
This release contains certain estimates and forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended, which are intended to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995, and may be identified by their use of words like “plans,” “expects,” “will,” “anticipates,” “believes,” “intends,” or other words of similar meaning. All statements that address expectations or projections about the future, including statements about Corteva’s expectations related to regulatory approvals, product development, product offerings and product, financial or sustainability performance are forward-looking statements. Corteva disclaims and does not undertake any obligation to update or revise any forward-looking statement, except as required by applicable law. A detailed discussion of some of the significant risks and uncertainties which may cause results and events to differ materially from such forward-looking statements or other estimates is included in the “Risk Factors” section of Corteva’s Annual Report on Form 10-K, as modified by subsequent reports on Form 10-Q and Current Reports on Form 8-K.

3/10/2023

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Media Contact

Larissa Capriotti
515-805-4857
larissa.capriotti@corteva.com